Though domestic duties connected to her 1811 marriage to von Arnim diminished her productivity, several art songs from the period have been recovered and have been published in Werke und Briefe. Von Arnim was the first composer to set the poet Hölderlin’s work to music.

She was a muse to the progressives of Prussia, linked to the socialist movement and an advocate for the oppressed Jewish community. She published two politically dissident works but evaded chastisement because of her friendship with the King of Prussia.